A 37 YEAR OLD FEMALE WITH FEVER , NECK PAIN AND ALTERED SENSORIUM

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.
37 year old female a resident of Dugapally , housewife was brought to the casuality with complaints of 
1. Neck pain since 4 days
2. Fever since 4 days
3. Body pains since 4 days
4. Altered sensorium since yesterday 

HOPI:

Patient  was apparently asymptomatic 4 days back then she had  neck pain which was insidious in onset and gradually progressive followed by burning of eyes then developed fever associated with chills and rigors din’t subside on medication 
patient’s attender took her to the local RMP for fever and was started on antibiotics.
Patient attender observed altered sensorium since yesterday and was brought to the hospital for further evaluation  

N/K/C/O HTN,DM,THYROID,ASTHMA,CAD

Surgical history: 

History of tympanoplasty 5 years ago 

On presentation:
patient is drowsy arousal to painful stimulus 

VITALS

febrile 101.3 F
B.P - 170/90 mm hg 
PR- 101 bpm
RR: 18 CPM

SYSTEMIC EXAMINATION 

Cvs - s1 s2 heard no murmurs
RS :- NVBS no adventitious sounds

Kernig’s sign positive 
Brudzinski’s sign positive 

Lumbar puncture was performed 


INVESTIGATIONS:

CSF ANALYSIS

TC -112 cells
Dc- predominantly lymphocytes
Rbc’s - Nil
Sugar-38
Protein -102
Chloride-98

BGT: O POSITIVE
APTT: 30 SEC
PT: 15 SEC
INR: 1.11

HEMOGRAM:

HB: 12.9 
TLC: 9,400
PLT: 3.39 L

LFT:

TB: 0.77
DB: 0.18
AST: 20
ALT: 35
ALP: 228
TP: 6.6
ALB: 3.7
A/G: 1.32

RFT:

S. Creat: 0.6
Na+ : 134
Cl- : 96
K+ : 3.0
URIC ACID: 1.8

BLOOD UREA: 17
RBS: 141 MG/DL

CUE:
COLOUR: PALE YELLOW, CLEAR
SP GRAVITY: 1.010
NO ALBUMIN/SUGARS/BILE PIGMENTS/BILE SALTS /RBC
PUS CELLS: 3-4
EPITHELIAL CELLS: 2-3

SPOT URINE PROTEIN: 7.5
SPOT URINE CREATININE : 44.2 
RATIO: 0.16


DIAGNOSIS :
TUBERCULAR MENINGITIS 

TREATMENT :

1. IVF NS and RL @ 75ml/ hour 
2. RT FEEDING 2nd hourly- 200ml 
3. Tab. RIFAMPICIN  600mg 
4. TAB. ISONIAZID 300 mg 
5. TAB. PYRAZINAMIDE 1500mg 
6. TAB. ETHAMBUTOL 1900 mg 
7. INJ. CEFTRIAXONE 2gm/IV/BD 
8. INJ. PAN 40 mg /IV/ BD 
9. INJ. ZOFER 4mg/ IV/SOS 
10. INJ. NEOMOL 100ml (if temp > 101.1F) 
11. Head end elevation by 30 degree
12. Vital monitoring hourly 
13. Fever charting 4th hourly


SOAP NOTES DAY 1:


S- no fresh complaints 


O- patient is drowsy 

Sensorium improved 

Not oriented to time/place/person 

Recalling her name 

Neck rigidity + 

Kernigs sign + 

Brudzinski sign + 

Pro did of the left eye lid 

Left conjunctival congestion And swelling present 


Vitals:

Temp: 99.1 F 

BP: 140/100 mmhg 

PR: 90bpm 

RR : 18cpm 

SPO2: 98% on RA 

I/O: 2700ml / 1050 ml 

Stools: not passed 


SYSTEMIC EXAMINATION: 


CVS: S1S2 present , no added sounds 

RS: BAE+ 

P/A: soft, non tender 


A- TB MENINGITIS 


P- 

1. IVF NS and RL @ 75ml/ hour 

2. RT FEEDING 2nd hourly- 200ml 

3. Tab. RIFAMPICIN  600mg 

4. TAB. ISONIAZID 300 mg 

5. TAB. PYRAZINAMIDE 1500mg 

6. TAB. ETHAMBUTOL 1900 mg 

7. INJ. CEFTRIAXONE 2gm/IV/BD 

8. INJ. PAN 40 mg /IV/ BD 

9. INJ. ZOFER 4mg/ IV/SOS 

10. INJ. NEOMOL 100ml (if temp > 101.1F) 

11. Head end elevation by 30 degree

12. Vital monitoring hourly 

13. Fever charting 4th hourly



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